Electrochemistry & Photochemistry

At TCG Lifesciences (TCGLS), we leverage advanced electrochemistry and photochemistry platforms to address complex synthetic challenges and enable innovative reaction pathways. By integrating photoredox catalysis and electrochemical methodologies into synthetic workflows, we support efficient, selective, and sustainable transformations for diverse chemical program.
Our capabilities are strengthened by advanced infrastructure, including Penn PhD Photoreactors and IKA ElectraSyn 2.0 Pro systems, enabling scalable, reproducible, and sustainable transformations for discovery and development programs.

Application of electrosynthetic methodologies to enable radical and redox-mediated organic transformations
Reactions performed using the IKA ElectraSyn 2.0 Pro electrochemical reactor, supporting controlled electrolysis across diverse electrode materials including graphite, platinum, nickel, zinc, magnesium, RVC foam, and glassy carbon
Supported transformations include radical addition, cyclization, ring-opening reactions, cross-coupling, and radical oxidation

Implementation of photoredox catalysis using multiple Penn PhD Photoreactor M2 systems across controlled wavelengths
Enables reproducible light-driven organic transformations for complex molecule synthesis
Representative reactions include contra-thermodynamic isomerization, stereoselective cyclization, cycloaddition, 1,2-addition, deoxygenative cross-coupling, and cyclopropanation

Electrochemistry