Palladium-Mediated Reductive Heck Cyclization for the Formation of Tricyclic Sultams

Published in: Journal, Volume : 26, Issue : 3, Pages : 359-362

DOI : 10.1055/s-0034-1379427

Author : Joardar, Soumen; Chakravorty, Santanu; Das, Saktipada

Abstract : Tricyclic sultams were synthesized through sulfonation and a palladium-mediated Sonogashira cross-coupling followed by a reductive Heck cyclization. The procedure is straightforward and was carried out under ligand-free conditions.